| 1. | Nonspecific barriers to fungal infection must be crossed , however , before specific immune responses to fungi are elicited
在特异性免疫反应产生之前，起作用的主要是非特异性的屏障结构。 |
| 2. | The trial ' s preliminary results indicate the vaccine was associated with tumor - specific immune response in patients with recurrent , high - grade glioma
研究结果初步显示疫苗可使复发的恶性胶质瘤患者产生肿瘤特异性免疫反应。 |
| 3. | Moreover , mice feeding on fmdv - vp1 transgenic plant leaves in their diet produced a virus - specific immune response that could protect the immunized mice against fmdv challenge
另外利用转基因植物表达口蹄疫病毒vp1抗原蛋白具有安全廉价、蛋白折叠充分、免疫原性良好等特点。 |
| 4. | The potency of capsaicin as an immuno - actie ligand together with its cytotoxic effects and the induction of a specific immune response could make it an attractie candidate for cancer immunotherapy
辣椒素具有免疫激活配体的潜能、细胞毒作用及特异免疫反应的诱导，以上三个作用使其成为癌症免疫治疗有吸引力的候选者。 |
| 5. | It delivers the false ? folding peptides for presentation to proteasomes in normal cells , while in tumor cells it acts as main tumor - resistant antigen , inducing specific immune response . recent research found that grp94 also relates with cell cycles , differentiation and apoptosis
此外发现它还具有抗原提呈作用，在正常细胞中参与折叠错误蛋白到蛋白酶体的提呈；在肿瘤细胞中作为主要的肿瘤排斥抗原，引发针对该肿瘤细胞的特异性免疫反应。 |
| 6. | We hope that our study will provide us with more comprehensive knowledge of the mechanisms of immune regulation and the roles that dc and complement play in innate and acquired immunity , as well as to lay a foundation for further exploration of the roles dc play in antigen - specific immune responses and immune tolerance from a new perspective . part i expression of complement receptors and complement - associated molecules on dendritic cells derived from distinct - origin at different stages of development two subsets of dendritic cells were generated from precursor cells isolated by means of magnetic cell separation system
曰补体受体及其相关分子在modc上的表达不同分化阶段的单核细胞衍生性dc ( monocytes一deriveddc ， modc )的诱导:将新鲜分离的单核细胞mo ，在含有gm一csf和工l一4培养体系中诱导5一7d ，即分化为未成熟modc ;对培养至sd的未成熟modc ，用tnfa刺激zd ，即分化为成熟modc ;此时再用lps刺激24h ，即为活化的modc 。 |
| 7. | In the first of 1990s , a new kind of vaccine - dna vaccine gives a new way to solve the immunogenicity of cea . it is defined as plasmids encoding antigen protein which can elicit immune responses against the antigen through direct injecting into body and taken into by cells , then , it stimulates the body generate specific immune response through different routes
核酸疫苗是指将含有编码肿瘤相关抗原基因的真核表达质粒，直接接种到动物体内，然后被动物细胞摄取并表达出相应的抗原，通过不同途径刺激机体产生针对该抗原的免疫应答，从而消除或抑制肿瘤细胞的生长。 |
| 8. | The fusion ( f ) protein and hemagglutinin - neuraminidase ( hn ) are the major virulence factors of the virus to which the host responds well with protective antibody production . recombinant plasmids containing the f or hn gene can induce specific immune responses against ndv . however , dna vaccination by injection or gene gun routes is rather inconvenient and costly in field applications in scaled animal farms
融合蛋白( f )和血凝素-神经氨酸酶蛋白( hn )是ndv的主要宿主保护性抗原，以f基因和hn基因为免疫原研制的dna疫苗能诱导一定程度的免疫应答，但注射免疫或基因枪免疫途径因实际操作和成本等问题难以推广应用，而直接口服重组质粒dna免疫效果不理想。 |
